Aptana - includes PyDev out of the box so you don't have to install it, very useful for those familiar with Eclipse and those that develop for Web and use python at the same time and want to keep it all in one place. Works also with IronPython.
Jet Brains PyCharm - an acclaimed commercial IDE with a lot of features was released for free only for python, makes me think that python was a good investment in the end. Works also with IronPython.
Light Table, smooth both in design and workflow, still at initial stages but I think it deserves a call.
Python Tools for Visual Studio - the only free version of Visual Studio and if you download the PTVS integrated with VS 2013 you can have the only free version of VS to my knowledge that works in one install and without any trouble, brings all the power of VS to python programming. Works also with IronPython and WPF.
I would really like to hear your subjective experience and what you like or not in some of these IDEs or other IDEs for that mater.
P.S.This is my first blog post in a while.